Capabilities

  • Characterization of Proteins and Peptides by charge, mass, molecular weight, HPLC, CD spectrometry, protease finger print, isoelectric point, Capillary Electrophoresis
  • Impurity profiling
  • Analytical method development and validation of the methods.
  • Part of the USP team with contribution towards creation of monographs for Biosimilar products

Infrastructure

Equipment for:

  • Identification of Proteins and Peptides
  • Peptide mapping
  • Impurity profiling
  • Glycoproteins and Carbohydrates analysis
  • Amino Acid Analyser
  • LCMS with interface ESI and APCI
  • HPLC with UV, refractive index and fluorescence detectors, elsd
  • GC with head space detection
  • Characterization of size variants in proteins using MALLS Detector
  • ESI-Q-TOF mass spectrometer with UPLC interface for accurate intact mass determination
  • Stability chambers
  • CD Spectropolarimeter
  • Dionex hplc system with IC and ECD detector
  • Plate Reader for ELISA and Protein Quantitation